- Jul 4, 2002
No there wasn't a significant risk in heart attack.There was a significant increase in cardiac arrest in patients receiving both hydroxychloroquine + azithromycin but not with either drug alone.That makes sense as both drugs lengthen the QT segment which can lead to a serious arrhythmia.And yet another study demonstrating no significant benefit and significant increased risk of heart attack.
Treatment With Hydroxychloroquine or Azithromycin and In-Hospital Mortality in Patients With COVID-19This study examines associations between use of hydroxychloroquine, azithromycin, or both and in-hospital mortality, ECG changes, and cardiac arrest among patients with COVID-19 hospitalized in the metropolitan New York area in March 2020.jamanetwork.com
But despite that there was no significant difference in mortality between those treated or not with this drug combination.There was even a trend to lower mortality with azithromycin alone.
On top of that the patients receiving the drugs had worse respiratory findings and a higher incidence of diabetes than those given neither drug.That is they were more likely to have a bad outcome.