General COVID-19 Vaccine Discussion

jakeseven7

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But there is no absolute proof that nRNA vaccines do not cause VIPIT or are safer than AZ.

With the mRNA vaccines there have also been reported cases of thrombocytopenia and bleeding.Now in HIT there are also some patients who bleed and this can include cerebral haemorrhage and so possible death.

As well the mRNA vaccines have a higher incidence of anaphylaxis which also can be fatal

And its now looking like the mRNA vaccines don't last as long as they hoped (well Pfizer at least) with boosters may be needed as early as 6 months....

No vaccine is perfect.
 

Lynda2475

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The burden of proof is on the claim that they definitely do, not that they definitely do not.

My friend had an anaphylactic reaction to moderna but has a history of reacting to all sorts of medicines and foods. The only thing that I have an anaphylactic reaction to is penicillin, my reading says Pfizer is safer for me, so that is what I will wait for.

All types of the vaccine will need booster shots, this has been known for quite a while. Its why I pointed out weeks ago my doubt that 2B will be vaccinated this year, as you can bet the Feds will want to give boosters to 1A before they start on 2B.

The annual flux vax only offers about 6 months protection, we just dont tend to bother with boosters over summer. I think most people expected to have to get a new one each year, and a 3rd this year due to variants.
 

HappyFlyerFamily

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According to Our World in Data, 950m jabs so far.

With a current rate of about 15m per day, the world will get to 1 billion in 4 days time.
 

Flashback

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Oxford about to kick off another trial, looking at mixing vaccines.

Still waiting for my email to be included in the trial..... let's see.

A dashboard depicting vaccine volunteers registered in the UK.
dashboard.png

1619124580730.png
 

teammongo

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But there is no absolute proof that nRNA vaccines do not cause VIPIT or are safer than AZ.

With the mRNA vaccines there have also been reported cases of thrombocytopenia and bleeding.Now in HIT there are also some patients who bleed and this can include cerebral haemorrhage and so possible death.

As well the mRNA vaccines have a higher incidence of anaphylaxis which also can be fatal
I don't think there are significant reports regarding mRNA vaccine VIPIT/VITTS. That editorial was mainly about Adenovirus vaccines.

Reports of an ITP like syndrome (idiopathic thrombocytopaenia purpura for those who aren't medics- a syndrome where your platelet count drops and get tiny bleeds under the skin that look like purple dots [purpura]) associated with mRNA vaccines are not clearly significant. An article by Lee, Cines et al in the American Journal of Hematology stated regarding mRNA vaccines - "Thus, the incidence of an immune-mediated thrombocytopenia post SARS-CoV-2 vaccination appears either less than or roughly comparable to what would be seen if the cases were coincidental following vaccination, perhaps enhanced somewhat by heightened surveillance of symptomatic patients."
"Distinguishing vaccine-induced ITP from coincidental ITP presenting soon after vaccination is impossible at this time."
ITP is very different from VITTS, with ITP essentially manifested as a lack of platelet function and primary haemorrhage - such as primary cerebral haemorrhage. VITTS is primarily a problem of platelet activation, thrombosis and secondary cerebral haemorrhage from venous hypertension, venous stroke and subsequent exogenous anticoagulation.

There were 35 possible cases of central nervous system thrombosis among 54 million Pfizer vaccinations, and 5 possible cases of cerebral venous sinus thrombosis among 4 million Moderna mRNA vaccinations. This is not appreciably higher (actually lower) than the expected community rate of cerebral sinus thrombosis of 0.22 to 1.57 cases per 100,000 per year.

So the risk of an event with an mRNA vaccine is vanishing rare and is actually lower than the chance of death by lightning strike (1 in 700,000).

TM
 

mviy

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Even if we had a facility ready to produce mRNA vaccines, Pfizer may not have licensed the vaccine to be produced here. Though a facility would enable trials for locally designed mRNA vaccine candidates to proceed.
 

lovetravellingoz

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Even if we had a facility ready to produce mRNA vaccines, Pfizer may not have licensed the vaccine to be produced here. Though a facility would enable trials for locally designed mRNA vaccine candidates to proceed.


Good article.

I think it all boils down to that mRNA manufacture in Australia is more a long-term, rather than short-term matter.

ie

If Seqirus develops its next generation mRNA-based influenza vaccine. that is when it will probably look to add mRNA manufacturing to portfolio. And that may not necessarily be at is new yet to built Melbourne plant.

“CSL is exploring future possibilities for mRNA vaccines within our portfolio and Seqirus, our influenza vaccines business, is working on the development of a next generation mRNA-based influenza vaccine. As always, we welcome discussions with governments as to how we can support Australia’s ongoing vaccination needs,” he said.
and
In a hearing of the senate select committee on COVID-19 on Tuesday, department of health secretary professor Brendan Murphy set setting up mRNA production capabilities in Australia would take at least one year.
“It’s quite a complex technology to set up, particularly the lipid nanoparticles in which the mRNA vaccines are suspended. That’s a very interesting proprietary technology. We would need to set this up from the ground up,” he said.
 

Must...Fly!

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jakeseven7

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1 jab is still enough to make a big difference (of course 2 jabs is better).

Yes prevents serious illness and hospitalisation which was the original goal, now who knows what the goal is. We haven’t been told :)
 

drron

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Although the evidence that vaccination prevents serious illness and deaths is strong for the UK and Israel but not so convincing for the USA.
1619389980643.png .
The number of infections is certainly way down but of those who have been vaccinated fully the incidence of being admitted to hospital is over 6% and of dying just over 1%.Those rates are not that much different to previous results in the USA.
 

MEL_Traveller

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The number of infections is certainly way down but of those who have been vaccinated fully the incidence of being admitted to hospital is over 6% and of dying just over 1%.Those rates are not that much different to previous results in the USA.

Are the figures on the 1% in terms of age? Is it still 10%+ for those over 80?
 

drron

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The numbers haven't been broken down by age but then the major sources of data have always been of countries overall data so comparison is fair.
 

Lynda2475

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but not so convincing for the USA.
Perhaps because, as SMH notes:

Millions of Americans are skipping their second doses of COVID vaccines​

By Rebecca Robbins​

New York: Millions of Americans are not getting the second doses of their COVID-19 vaccines, and their ranks are growing.

More than 5 million people, or nearly 8 per cent of those who got a first shot of the Pfizer or Moderna vaccines, have missed their second doses, according to the most recent data from the Centres for Disease Control and Prevention.

That is more than double the rate among people who got inoculated in the first several weeks of the nationwide vaccine campaign.
 

Must...Fly!

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More than 5 million people, or nearly 8 per cent of those who got a first shot of the Pfizer or Moderna vaccines, have missed their second doses, according to the most recent data from the Centres for Disease Control and Prevention.
I have heard the first jab protects you, but the second one contains the 5G microchip

/s
 

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