My guess would be on one of the following:
- Weird sudden confusion and/or medical drama- wouldn't we know about the latter by now though?
- Medical issue due to a condition that the pilot was very well aware but was trying to hide in order to stay in his job (not that unlikely tbh)
- Malicious intent (which would be god awful but nothing surprises anymore in this respect...)
- Some weird technical glitch that somehow leads to showing inputs and brakes activating while this was actually not caused by the pilot (not sure if this is even possible- I'm not a technical expert AT ALL).
Anything else I missed? Form everything we've heard so far, it does not sound as if the crew was aware of what caused it (or at least pretended not to be aware...).