I recently flew SYD-BKK-SYD on a QF 333. I wouldn't say it was a great experience but not super uncomfortable.
The 2-4-2 config in Y is good. Only one away from the aisle so getting out for a leak or a stretch isn't such a big deal.
Entertainment screens are a decent size and have powered outlets, plus an AC socket below (shared between two seats). I was able to use my AirFly to pump put Bluetooth to my wireless headphones. Wired headphones are provided.
Good choice of movies and videos. No audio, apart from a few audiobooks.
You get a pillow and blanket for night flights. With a window seat, the pillow can be wedged against the window. The blanket I found most useful for cushioning my feat. There is no feet net as in the A380 seat.
Food is reasonably awful or okay. You won't starve. Unhealthy snacks are handed out at intervals between meals.
Individual plastic wine bottles are served. You can try for a suggested pairing but don't expect too much. It's not bad but you probably won't be hitting up
Dan Murphy's for a crate of it on return home.
Get a good playlist on your device, some eyeshades, painkillers, wireless headphones, you'll be okay.