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Message: <blockquote data-quote="Quickstatus" data-source="post: 2334517" data-attributes="member: 49035">But yet you quoted a booster study which suggested that boosters had a difference - did you read that study? It used PZ as the booster.The Study did say that booster resulted in a similar vaccine effectiveness compared to when 2 Jabs were fresh. It didn’t do a 2 group comparison looking at 2 jab no booster and 2 jab+booster groups at the same point in time. Also the Delta wave had just past conferring further immunity on large swathes of the population. What it doesn’t say is how long that lasts for. Are we to have boosters every 5 months for the rest of our lives?There are many limitations to that studyOne, it was done in Sept 2021 after the Delta wave but before the Omicrom wave and the rest - see “limitations” sectionThe best intepretation is that boosters do return vaccine effectiveness to the peak levels of the 2 jabs but like the 2jabs (from other studies) will wane over time. From my point of view, I think boosters bang for buck lies in yearly pre winter jabs for the vulnerable. For the young, healthy, it would be diminishing returns .</blockquote>